Active supercoiling induction in plasmid suspensions creates branched conformations and locks threaded entanglements into slowly relaxing clusters.
Giesinger, The existence and formation dynam- ics of supramolecular chains in equilibrated and sheared ring polymer melts, Master’s thesis, University of Vienna (2025)
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Actively induced supercoiling can slow down plasmid solutions by trapping the threading entanglements
Active supercoiling induction in plasmid suspensions creates branched conformations and locks threaded entanglements into slowly relaxing clusters.