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arxiv: 2604.14955 · v1 · submitted 2026-04-16 · 🪐 quant-ph

Recognition: unknown

Three ways to share a QPU: Scheduling strategies for hybrid Quantum-HPC applications

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Pith reviewed 2026-05-10 10:36 UTC · model grok-4.3

classification 🪐 quant-ph
keywords hybrid quantum-classical computingHPC schedulingQPU sharingmalleabilityworkflow decompositiontime multiplexingresource optimization
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The pith

Malleability and workflow strategies cut classical resource use in balanced hybrid quantum-HPC jobs by up to 64 percent while time-multiplexing maximizes QPU sharing for imbalanced cases.

A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.

The paper examines three approaches to scheduling hybrid quantum and classical computations on shared HPC systems that have scarce quantum processors. It shows that malleability and workflow decomposition save the largest amounts of classical computing resources when quantum and classical workloads are roughly equal, whereas running jobs sequentially in time slots improves quantum processor utilization and shortens overall cluster runtimes when one workload dominates. Readers care because quantum hardware is still limited and expensive, so effective sharing determines how many practical hybrid applications can run at scale. The experiments on real production clusters and quantum devices indicate that the three methods are complementary rather than alternatives. No single strategy works best in all situations, so the choice must depend on the balance of the specific job.

Core claim

Malleability and workflow strategies significantly optimize classical resource utilization, reducing consumption by up to 45.7% and 64% respectively, proving to be best fitted for hybrid jobs where quantum and classical workloads are evenly balanced. Conversely, time-multiplexing enhances QPU utilization and reduces execution time at the cluster level, making it the optimal strategy for the opposite context, which is characterized by high classical-quantum workload imbalances. Experimental validation on production HPC clusters and real quantum hardware demonstrates the effectiveness of these approaches under different workload scenarios.

What carries the argument

Three methodologies for HPC-QC resource scheduling: time-based multiplexing, dynamic resource management, and workflow decomposition. These address mismatches between quantum and classical models plus the scarcity of QPUs by controlling how jobs share heterogeneous resources.

Load-bearing premise

The tested workload scenarios and hardware setups are representative of real-world hybrid quantum-classical applications and that the observed resource savings will generalize beyond the specific production clusters and quantum devices used.

What would settle it

Applying the same three scheduling strategies to a fresh collection of hybrid applications on a different production cluster and real quantum hardware, then checking whether classical resource reductions and QPU utilization gains reach or exceed the reported levels.

Figures

Figures reproduced from arXiv: 2604.14955 by Alberto Scionti, Andrea Muratori, Antonio J. Pe\~na, Bartolomeo Montrucchio, Chiara Vercellino, Daniele Gregori, Daniele Ottaviani, Elisabetta Boella, Emanuele Dri, Fulvio Ganz, Gabriella Bettonte, Giacomo Vitali, Iacopo Colonnelli, Jonathan Frassineti, Marco Cipollini, Matteo Barbieri, Olivier Terzo, Orazio Spina, Paolo Viviani, Petter Sand{\aa}s, Roberto Rocco, Sara Marzella, Sergio Iserte, Simone Rizzo.

Figure 1
Figure 1. Figure 1: Positioning of the three proposed scheduling strate￾gies along two orthogonal axes: the time-scale granularity at which quantum and classical workloads alternate (horizontal) and the degree of programming-model transparency, i.e., the extent to which the application must be explicitly restructured to benefit from the strategy (vertical). run in standard partitions and enabling malleability without interfer… view at source ↗
Figure 2
Figure 2. Figure 2: An illustrative example of the execution of two hybrid jobs, following the naïve co-scheduling policy. The upper/lower row represents the timeline of classical/quantum computations. Since there is only one available QPU in the system, the first submitted job holds it for its entire duration, preventing the second one to even begin its classical computations. This ultimately leads to a major under-utilizati… view at source ↗
Figure 3
Figure 3. Figure 3: A representation of the execution of the same two hybrid jobs in [PITH_FULL_IMAGE:figures/full_fig_p005_3.png] view at source ↗
Figure 4
Figure 4. Figure 4: A (1,5)-clustered graph used as input to the GC problem. The central node (label 4) is the vertex separator of 2 clusters with 5 nodes each. Circuit Cutting. Given the limited number of qubits avail￾able on the quantum device, the circuit cutting technique was employed to enable the execution of circuits involving more than 5 qubits [61]. Circuit cutting allows a quantum circuit to be decomposed into small… view at source ↗
Figure 5
Figure 5. Figure 5: The QAOA circuit used to solve a MIS instance for the graph in [PITH_FULL_IMAGE:figures/full_fig_p009_5.png] view at source ↗
Figure 6
Figure 6. Figure 6: Data and processes of the target application. Yellow shapes are data between processes, green boxes are classical processes, and purple boxes are processes suitable to be performed by quantum resources. The application loops until the Silhouette score of a certain clustering reaches a user￾defined threshold or until the maximum number of loop iterations is reached. than quantum algorithmic performance, we … view at source ↗
Figure 7
Figure 7. Figure 7: The plots depicting Quantum Occupancy (a), Quantum Time (b) and Mean Queue Time (c) with respect to an increasing number of concurrent GC replicas (𝑛_𝑐𝑜𝑝𝑖𝑒𝑠). The labels 𝑅 ∈ {0, 2, 5} refer to runs with a different quantum￾classical workload ratio set, as explained at the beginning of Section 4.3.1. The 𝑦 = 𝑎 ⋅ 𝑥 dashed line in Sub-figure (b) is used to highlight the linearity relation of the data. node fr… view at source ↗
Figure 8
Figure 8. Figure 8: The plots depicting Total Time and Job Runtimes Distribution metrics. The vertical axis is set on a log scale for plots (d.1-3), while a regular linear scale is used for plots (e.1-3). Note that we disregard here the quantum resources, as their usage is constant across the three scenarios. The dataset used in the clustering application consists of 80,000 2D points generated via make_blobs from scikit￾learn… view at source ↗
Figure 9
Figure 9. Figure 9: Timeline of cumulative usage of classical nodes on our Slurm compute partition when launching two concurrent workloads (in blue and orange, respectively) with two minutes long quantum jobs. Each subplot refers to a different schedul￾ing approach, i.e. baseline, workflow, and malleability. ending workload, thus considering two complete end-to-end simulations. The baseline approach is, in this case, the wors… view at source ↗
read the original abstract

As quantum computing (QC) technologies mature, their integration into established high-performance computing (HPC) infrastructures is becoming a central objective for next-generation computing systems. However, unlocking the potential of hybrid platforms for computationally demanding workloads remains challenging. The mismatch between quantum and classical programming models, the limited maturity of quantum software stacks, and the scarcity of quantum processing units (QPUs) above all, necessitate scheduling strategies that go beyond standard HPC mechanisms to manage such heterogeneous and constrained resources. To address this issue, we investigate three distinct methodologies for HPC-QC resource scheduling: time-based multiplexing, dynamic resource management, and workflow decomposition. Experimental validation on production HPC clusters and real quantum hardware demonstrates the effectiveness of these approaches under different workload scenarios. Malleability and workflow strategies significantly optimize classical resource utilization, reducing consumption by up to 45.7% and 64% respectively, proving to be best fitted for hybrid jobs where quantum and classical workloads are evenly balanced. Conversely, time-multiplexing enhances QPU utilization and reduces execution time at the cluster level, making it the optimal strategy for the opposite context, which is characterized by high classical-quantum workload imbalances. These findings underscore the practical viability of tailored scheduling strategies for hybrid HPC-QC environments and highlight their complementarity in building efficient, scalable software stacks for next-generation quantum-accelerated facilities.

Editorial analysis

A structured set of objections, weighed in public.

Desk editor's note, referee report, simulated authors' rebuttal, and a circularity audit. Tearing a paper down is the easy half of reading it; the pith above is the substance, this is the friction.

Referee Report

2 major / 1 minor

Summary. The paper investigates three scheduling strategies for hybrid Quantum-HPC applications—time-based multiplexing, dynamic resource management (malleability), and workflow decomposition—on production HPC clusters and real quantum hardware. It claims that malleability and workflow strategies optimize classical resource utilization with reductions up to 45.7% and 64% respectively and are best suited for evenly balanced quantum-classical workloads, while time-multiplexing improves QPU utilization and reduces cluster-level execution time for imbalanced workloads.

Significance. If the results hold under broader conditions, the work provides practical empirical guidance on tailoring scheduling to workload balance in emerging hybrid systems and demonstrates the complementarity of the three approaches. The use of real quantum hardware alongside production clusters is a clear strength, as is the focus on measurable resource metrics rather than purely theoretical models.

major comments (2)
  1. [Abstract] Abstract: The central claims of up to 45.7% and 64% reductions in classical resource consumption, plus the ranking of strategies as 'best fitted' for balanced vs. imbalanced workloads, are stated without any description of workload definitions, the quantum-classical balance ratios tested, measurement methods, error bars, baseline comparisons, or statistical significance. These omissions are load-bearing for the performance conclusions.
  2. [Experimental validation] Experimental validation: No quantitative details are supplied on the workload generator, number of runs, hardware parameters (qubit count, coherence times, queueing policies), or how the observed ordering of strategies was determined. This directly affects whether the reported savings and optimality rankings can be assessed for robustness.
minor comments (1)
  1. [Introduction] The introduction could more explicitly define 'malleability' and 'workflow decomposition' before the experimental claims are introduced.

Simulated Author's Rebuttal

2 responses · 0 unresolved

We thank the referee for the constructive and detailed feedback on our manuscript. We have carefully reviewed the major comments and provide point-by-point responses below, indicating the revisions we will make to address the concerns raised.

read point-by-point responses
  1. Referee: [Abstract] Abstract: The central claims of up to 45.7% and 64% reductions in classical resource consumption, plus the ranking of strategies as 'best fitted' for balanced vs. imbalanced workloads, are stated without any description of workload definitions, the quantum-classical balance ratios tested, measurement methods, error bars, baseline comparisons, or statistical significance. These omissions are load-bearing for the performance conclusions.

    Authors: We agree that the abstract would benefit from additional context to support the central claims. In the revised manuscript, we will expand the abstract to briefly define the workload types (balanced workloads with comparable quantum and classical resource demands versus imbalanced workloads with significant classical dominance), specify the tested quantum-classical balance ratios, describe the resource measurement approach using HPC accounting tools, and note that the reported reductions include comparisons to baseline scheduling with associated variability measures detailed in the experimental results. This revision will directly address the concerns while preserving the abstract's conciseness. revision: yes

  2. Referee: [Experimental validation] Experimental validation: No quantitative details are supplied on the workload generator, number of runs, hardware parameters (qubit count, coherence times, queueing policies), or how the observed ordering of strategies was determined. This directly affects whether the reported savings and optimality rankings can be assessed for robustness.

    Authors: We recognize the importance of providing comprehensive experimental details for reproducibility and assessment of robustness. While the manuscript outlines the overall experimental framework using production HPC clusters and real quantum hardware, we will revise the experimental validation section to include quantitative specifications of the workload generator, the number of runs conducted for each configuration, relevant hardware parameters including qubit counts and coherence times, the queueing policies employed, and the criteria and methods used to establish the ordering of strategies (such as direct metric comparisons). These additions will enable a more thorough evaluation of the results. revision: yes

Circularity Check

0 steps flagged

No circularity: empirical scheduling comparisons with measured results, no derivations or fitted models

full rationale

The paper reports experimental validation of three scheduling strategies (time-multiplexing, dynamic resource management, workflow decomposition) on production HPC clusters and real quantum hardware. It presents measured outcomes such as up to 45.7% and 64% reductions in classical resource consumption under specific workload scenarios. No equations, derivations, parameter fittings, or self-citation chains are invoked to support the central claims; the results are direct observations from the described experiments. The reader's assessment of 0.0 circularity is consistent with the absence of any load-bearing step that reduces by construction to prior inputs. Generalization concerns (representativeness of workloads) are separate from circularity and do not involve self-referential definitions or renamings.

Axiom & Free-Parameter Ledger

0 free parameters · 0 axioms · 0 invented entities

No free parameters, axioms, or invented entities are introduced; the work relies on standard assumptions about workload representativeness and hardware accessibility that are not formalized.

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Reference graph

Works this paper leans on

88 extracted references · 56 canonical work pages · 1 internal anchor

  1. [1]

    Quantum-centricsupercomputingformateri- alsscience:Aperspectiveonchallengesandfuturedirections

    Alexeev, Y., Amsler, M., Barroca, M.A., Bassini, S., Battelle, T., Camps,D.,etal.,2024. Quantum-centricsupercomputingformateri- alsscience:Aperspectiveonchallengesandfuturedirections. Future Generation Computer Systems 160, 666–710

  2. [2]

    Aperspectiveonquantumcomputingapplica- tions in quantum chemistry using 25–100 logical qubits

    Alexeev, Y., Batista, V.S., Bauman, N., Bertels, L., Claudino, D., Dutta,R.,etal.,2025. Aperspectiveonquantumcomputingapplica- tions in quantum chemistry using 25–100 logical qubits. Journal of Chemical Theory and Computation 21, 11335–11357. doi:10.1021/ acs.jctc.5c01038

  3. [3]

    Aliaga, J.I., Castillo, M., Iserte, S., Martín-Álvarez, I., Mayo, R.,

  4. [4]

    Applied Science 12, 1–32

    A Survey on Malleability Solutions for High-Performance Distributed Computing. Applied Science 12, 1–32. doi:10.3390/ app12105231

  5. [6]

    Humble, Ryan Landfield, Ketan Mahesh- wari, Sarp Oral, Michael A

    Beck, T., Baroni, A., et al., 2024. Integrating quantum computing resourcesintoscientifichpcecosystems.FutureGenerationComputer Systems 161, 11–25. doi:10.1016/j.future.2024.06.058

  6. [7]

    Beránek, J., Böhm, A., Palermo, G., Martinovič, J., Jansík, B.,

  7. [8]

    SoftwareX 27, 101814

    Hyperqueue: Efficient and ergonomic task graphs on hpc clusters. SoftwareX 27, 101814. URL:https://www.sciencedirect. com/science/article/pii/S2352711024001857,doi:https://doi.org/10. 1016/j.softx.2024.101814

  8. [9]

    Optimalwirecuttingwith classical communication, 2023

    Brenner,L.,Piveteau,C.,Sutter,D.,2023. Optimalwirecuttingwith classical communication, 2023. arXiv preprint arXiv:2302.03366

  9. [10]

    High-performance computing with quantum processing units

    Britt, K.A., Humble, T.S., 2017. High-performance computing with quantum processing units. ACM Journal on Emerging Technologies in Computing Systems (JETC) 13, 1–13

  10. [11]

    The role of quantum computing in advanc- ing scientific high-performance computing: A perspective from the ADAC institute

    Buchs, G., Beck, T., Bennink, R., Claudino, D., Delgado, A., Fadel, N.A., et al., 2026. The role of quantum computing in advanc- ing scientific high-performance computing: A perspective from the ADAC institute. Future Generation Computer Systems 182, 108487. doi:10.1016/j.future.2026.108487

  11. [12]

    Burgholzer,L.,Echavarria,J.,Hopf,P.,Stade,Y.,Rovara,D.,Schmid, L., et al., 2026. The munich quantum software stack: Connecting end users, integrating diverse quantum technologies, accelerating hpc, in: Proceedings of the Supercomputing Asia and International ConferenceonHighPerformanceComputinginAsiaPacificRegion, pp. 55–67

  12. [13]

    Register allocation via coloring

    Chaitin, G.J., Auslander, M.A., Chandra, A.K., Cocke, J., Hopkins, M.E., Markstein, P.W., 1981. Register allocation via coloring. Com- puter languages 6, 47–57

  13. [14]

    Virtual qpu experiments.https: //gitlab.linksfoundation.com/aca/quantum-computing/ virtual-qpu-experiments

    Cipollini, M., 2026. Virtual qpu experiments.https: //gitlab.linksfoundation.com/aca/quantum-computing/ virtual-qpu-experiments

  14. [15]

    Colonnelli, I., 2023. Workflow models for heterogeneous distributed systems, in: Proceedings of the 2nd Italian Conference on Big Data and Data Science (ITADATA 2023), Naples, Italy, September 11- 13, 2023, CEUR-WS.org. URL:https://ceur-ws.org/Vol-3606/ invited77.pdf

  15. [16]

    IEEE Trans

    Colonnelli,I.,Cantalupo,B.,Merelli,I.,Aldinucci,M.,2021.Stream- flow: Cross-breeding cloud with HPC. IEEE Trans. Emerg. Top. Comput. 9, 1723–1737. doi:10.1109/TETC.2020.3019202

  16. [17]

    Federated learning meets HPC and cloud, in: Astrophysics and Space Science Proceedings, Springer

    Colonnelli, I., Casella, B., Mittone, G., Arfat, Y., Cantalupo, B., Esposito, R., Martinelli, A.R., Medić, D., Aldinucci, M., 2023. Federated learning meets HPC and cloud, in: Astrophysics and Space Science Proceedings, Springer. p. 193–199. doi:10.1007/ 978-3-031-34167-0_39

  17. [18]

    Colonnelli, I., Medić, D., Mulone, A., Bono, V., Padovani, L., Ald- inucci, M., 2024. Introducing SWIRL: an intermediate representa- tion language for scientific workflows, in: Formal Methods - 26th International Symposium, FM 2024, Milan, Italy, September 9-13, 2024, Proceedings, Part I, Springer. pp. 226–244. doi:10.1007/ 978-3-031-71162-6\_12

  18. [19]

    Infrastructure and API extensions for elastic execution of MPI appli- cations, in: 23rd EuroMPI, pp

    Comprés, I., Mo-Hellenbrand, A., Gerndt, M., Bungartz, H.J., 2016. Infrastructure and API extensions for elastic execution of MPI appli- cations, in: 23rd EuroMPI, pp. 82–97

  19. [21]

    Crusoe, M.R., Abeln, S., Iosup, A., Amstutz, P., Chilton, J., et al.,

  20. [22]

    Communication of the ACM doi:10.1145/3486897

    Methods included: Standardizing computational reuse and portability with the common workflow language. Communication of the ACM doi:10.1145/3486897

  21. [23]

    Das, P., Tannu, S.S., Nair, P.J., Qureshi, M., 2019. A case for multi-programming quantum computers, in: Proceedings of the 52nd Annual IEEE/ACM International Symposium on Microarchitecture, Association for Computing Machinery, New York, NY, USA. p. 291–303. doi:10.1145/3352460.3358287

  22. [24]

    Rigoletto: A workflow definition language for hybrid quantum-classical scientific applica- tions,in:202426thInternationalConferenceonBusinessInformatics (CBI), pp

    De Maio, V., Bork, D., Brandic, I., 2024. Rigoletto: A workflow definition language for hybrid quantum-classical scientific applica- tions,in:202426thInternationalConferenceonBusinessInformatics (CBI), pp. 40–49. doi:10.1109/CBI62504.2024.00015

  23. [25]

    A survey on integrating quantum computers into high performance computing systems,

    Döbler, P., Jattana, M.S., 2025. A survey on integrating quantum computers into high performance computing systems. URL:https: M. Cipollini, S. Rizzo et al.:Preprint submitted to ElsevierPage 16 of 18 Three ways to share a QPU //arxiv.org/abs/2507.03540,arXiv:2507.03540

  24. [26]

    Seitz, M

    Elsharkawy, A., Guo, X., Schulz, M., 2024. Integration of quantum accelerators into hpc: Toward a unified quantum platform, in: 2024 IEEE International Conference on Quantum Computing and Engi- neering (QCE), pp. 774–783. doi:10.1109/QCE60285.2024.00097

  25. [27]

    Distribution of entanglement in two-dimensional square grid network,

    Elsharkawy, A., To, X.T.M., Seitz, P., Chen, Y., Stade, Y., Geiger, M., et al., 2023. Challenges in hpcqc integration, in: 2023 IEEE International Conference on Quantum Computing and Engineering (QCE), pp. 405–406. doi:10.1109/QCE57702.2023.10304

  26. [28]

    Hybrid classical-quantum cluster- ing aggregation.https://github.com/E4-Computer-Engineering/ clustering-mis

    Engineering, E.C., 2025. Hybrid classical-quantum cluster- ing aggregation.https://github.com/E4-Computer-Engineering/ clustering-mis

  27. [29]

    Slurm heterogeneous jobs for hybrid classical-quantum workflows.arXiv:2506.03846

    Esposito, A., Haus, U.U., 2025. Slurm heterogeneous jobs for hybrid classical-quantum workflows.arXiv:2506.03846

  28. [31]

    Ester, M., Kriegel, H.P., Sander, J., Xu, X., 1996. A density-based algorithm for discovering clusters in large spatial databases with noise, in: Proceedings of the Second International Conference on Knowledge Discovery and Data Mining, AAAI Press. p. 226–231

  29. [32]

    A Quantum Approximate Optimization Algorithm

    Farhi, E., Goldstone, J., Gutmann, S., 2014. A quantum approximate optimization algorithm. arXiv preprint arXiv:1411.4028

  30. [33]

    Packing Schemes for Gang Scheduling, in: Proceedings of the Workshop on Job Scheduling Strategies for ParallelProcessing,Springer-Verlag,Berlin,Heidelberg.pp.89–110

    Feitelson, D.G., 1996. Packing Schemes for Gang Scheduling, in: Proceedings of the Workshop on Job Scheduling Strategies for ParallelProcessing,Springer-Verlag,Berlin,Heidelberg.pp.89–110

  31. [34]

    Workflows Community Summit 2022: A Roadmap Revolution

    Ferreira Da Silva, R., Badia, R., Bala, V., Bard, D., Bremer, P.T., Buckley, I., et al., 2023. Workflows Community Summit 2022: A Roadmap Revolution. Technical Report. Oak Ridge National Labo- ratory(ORNL),OakRidge,TN(UnitedStates). doi:10.2172/2006942

  32. [35]

    Hamamura, I., Imamura, T., Arakawa, T., Sumimoto, S., Yamazaki, K., Hu, Y., et al., 2026. Integrating quantum and hpc: A prototype hybrid implementation and benchmark of quantum-selected config- uration interaction, in: Proceedings of the Supercomputing Asia and International Conference on High Performance Computing in Asia Pacific Region Workshops, pp. 208–218

  33. [36]

    Improving quantum and classi- cal decomposition methods for vehicle routing

    Herzog, L.S., Wagner, F., Ufrecht, C., Palackal, L., Plinge, A., Mutschler, C., et al., 2024. Improving quantum and classi- cal decomposition methods for vehicle routing. arXiv preprint arXiv:2404.05551

  34. [37]

    Huber, S

    Huber, D., Iserte, S., Schreiber, M., Peña, A.J., Schulz, M., 2025. Bridging the Gap Between Genericity and Programmability of Dy- namic Resources in HPC, in: ISC High Performance 2025 Research Paper Proceedings (40th International Conference), pp. 1–11. URL: https://ieeexplore.ieee.org/document/11018304

  35. [38]

    Quantum Computers for High-Performance Computing

    Humble, T.S., McCaskey, A., et al., 2021. Quantum Computers for High-Performance Computing. IEEE Micro 41, 15–23. doi:10.1109/ MM.2021.3099140

  36. [39]

    High-throughput Computation through Efficient Resource Management

    Iserte, S., 2018. High-throughput Computation through Efficient Resource Management. Ph.D. Thesis. Universitat Jaume I. doi:10. 6035/14101.2018.176272

  37. [40]

    Malleable computational fluid dynamics simulations, in: Proceedings of the 36th Parallel CFD International Conference, Merida, Yucatan, Mexico

    Iserte, S., Houzeaux, G., Sandås, P., Peña, A.J., Garcia-Gasulla, M., 2025a. Malleable computational fluid dynamics simulations, in: Proceedings of the 36th Parallel CFD International Conference, Merida, Yucatan, Mexico

  38. [41]

    Turner, J

    Iserte,S.,Madon,M.,DaCosta,G.,Pierson,J.M.,Peña,A.J.,2025b. MPI malleability validation under replayed real-world HPC condi- tions. Future Generation Computer Systems , 108305doi:10.1016/j. future.2025.108305

  39. [42]

    ResourceoptimizationwithMPIprocess malleability for dynamic workloads in HPC clusters

    Iserte, S., Martín-Álvarez, I., Rojek, K., Aliaga, J.I., Castillo, M., Folwarska,W.,etal.,2025c. ResourceoptimizationwithMPIprocess malleability for dynamic workloads in HPC clusters. Future Genera- tion Computer Systems , 107949doi:10.1016/j.future.2025.107949

  40. [43]

    Dynamic Reconfiguration of Non-iterative Scientific Applications: A Case Study with HPG-aligner

    Iserte, S., Martínez, H., Barrachina, S., Castillo, M., Mayo, R., Peña, A.J., 2018a. Dynamic Reconfiguration of Non-iterative Scientific Applications: A Case Study with HPG-aligner. International Journal of High Performance Computing Application 33, 1–10. doi:10.1177/ 1094342018802347

  41. [44]

    DMR API: Improving Cluster Productivity by Turning Applications into Malleable

    Iserte, S., Mayo, R., Quintana-Ortí, E.S., Beltran, V., Peña, A.J., 2018b. DMR API: Improving Cluster Productivity by Turning Applications into Malleable. Parallel Computing 78, 54–66. doi:10. 1016/j.parco.2018.07.006

  42. [45]

    Flow problems in multi- interface networks.IEEE Transactions on Computers, 63:361–374, 2014

    Iserte, S., Mayo, R., Quintana-Ortí, E.S., Peña, A.J., 2020. DMRlib: Easy-codingandEfficientResourceManagementforJobMalleability. IEEE Transactions on Computers 70, 1443–1457. doi:10.1109/TC. 2020.3022933

  43. [46]

    A Study of the Effect of Process MalleabilityintheEnergyEfficiencyonGPU-basedClusters

    Iserte, S., Rojek, K., 2020. A Study of the Effect of Process MalleabilityintheEnergyEfficiencyonGPU-basedClusters. Journal of Supercomputing 76, 255–274. doi:10.1007/s11227-019-03034-x

  44. [47]

    Graphcoloringproblems

    Jensen,T.R.,Toft,B.,2011. Graphcoloringproblems. JohnWiley& Sons

  45. [48]

    Pascuzzi, Zhihao Xu, Tengfei Luo, Eungkyu Lee, and In-Saeng Suh

    Kim,S.,Pascuzzi,V.R.,Xu,Z.,Luo,T.,Lee,E.,Suh,I.S.,2025. Dis- tributed quantum approximate optimization algorithm on a quantum- centric supercomputing architecture.arXiv:2407.20212

  46. [49]

    Performance analysis of an optimization algorithmformetamaterialdesignontheintegratedhigh-performance computing and quantum systems.arXiv:2405.02211

    Kim, S., Suh, I.S., 2024. Performance analysis of an optimization algorithmformetamaterialdesignontheintegratedhigh-performance computing and quantum systems.arXiv:2405.02211

  47. [50]

    Stains,et al., Anatomy of STEM Teaching in American Universities: A Snapshot from a Large-Scale Observation Study.Science359(6383), 1468–1470 (2018), doi:10.1126/science

    Kirkpatrick, S., Gelatt, C.D., Vecchi, M.P., 1983. Optimization by simulated annealing. Science 220, 671–680. doi:10.1126/science. 220.4598.671

  48. [51]

    Recording provenance of workflow runs with ro-crate

    Leo, S., Crusoe, M.R., Rodríguez-Navas, L., Sirvent, R., Kanitz, A., Geest, P.D., Wittner, R., Pireddu, L., Garijo, D., Fernández, J.M., Colonnelli, I., Gallo, M., Ohta, T., Suetake, H., Capella-Gutierrez, S., de Wit, R., Kinoshita, B.P., Soiland-Reyes, S., 2024. Recording provenance of workflow runs with ro-crate. PLoS ONE 19, 1–35. doi:10.1371/journal.p...

  49. [52]

    Clustering aggregation as maximum- weight independent set, in: Neural Information Processing Systems

    Li, N., Latecki, L.J., 2012. Clustering aggregation as maximum- weight independent set, in: Neural Information Processing Systems. URL:https://api.semanticscholar.org/CorpusID:7043357

  50. [53]

    Liu, L., Dou, X., 2021. Qucloud: A new qubit mapping mechanism for multi-programming quantum computing in cloud environment, in:2021IEEEInternationalSymposiumonHigh-PerformanceCom- puter Architecture (HPCA), pp. 167–178. doi:10.1109/HPCA51647. 2021.00024

  51. [54]

    DynQ: A dynamic topology- agnostic quantum virtual machine via quality-weighted community detection.arXiv:2601.19635

    Liu, S., Elahi, P.J., Varetto, U., 2026. DynQ: A dynamic topology- agnostic quantum virtual machine via quality-weighted community detection.arXiv:2601.19635

  52. [55]

    Fast quantum circuit cutting with randomized measurements

    Lowe, A., Medvidović, M., Hayes, A., O’Riordan, L.J., Bromley, T.R., Arrazola, J.M., et al., 2023. Fast quantum circuit cutting with randomized measurements. Quantum 7, 934

  53. [56]

    Multivariateobservations,in:Proceedingsofthe 5th Berkeley Symposium on Mathematical Statisticsand Probability, pp

    MacQueen,J.,1967. Multivariateobservations,in:Proceedingsofthe 5th Berkeley Symposium on Mathematical Statisticsand Probability, pp. 281–297

  54. [57]

    Mansfield, E., Seegerer, S., Vesanen, P., Echavarria, J., Farooqi, M.N., Mete, B., et al., 2025. First practical experiences integrating quantumcomputerswithhpcresources:Acasestudywitha20-qubit superconducting quantum computer, in: Proceedings of the SC ’25 Workshops of the International Conference for High Performance Computing,Networking,StorageandAnaly...

  55. [58]

    Mantha, F

    Mantha,P.,Kiwit,F.J.,Saurabh,N.,Jha,S.,Luckow,A.,2024. Pilot- Quantum: A quantum-HPC middleware for resource, workload and task management.arXiv:2412.18519

  56. [59]

    Robust ultra-shallow shadows,

    McCaskey,A.J.,Lyakh,D.I.,etal.,2020.XACC:Asystem-levelsoft- ware infrastructure for heterogeneous quantum–classical computing. QuantumScienceandTechnology5,024002. doi:10.1088/2058-9565/ ab6bf6

  57. [60]

    mlco2/codecarbon: v2.4.1,

    Michielsen,K.,Bartsch,V.,MARCHESIN,ANDREA.,DENIEL,P., Johansson,M.,Vitali,G.,etal.,2025.ETP4HPCSRA6WhitePaper- QuantumforHPC.TechnicalReport.ETP4HPC.doi:10.5281/ZENODO. 14628871

  58. [61]

    fastcluster: Fast hierarchical, agglomerative clus- tering routines for R and Python

    Müllner, D., 2013. fastcluster: Fast hierarchical, agglomerative clus- tering routines for R and Python. Journal of Statistical Software 53. M. Cipollini, S. Rizzo et al.:Preprint submitted to ElsevierPage 17 of 18 Three ways to share a QPU doi:10.18637/jss.v053.i09

  59. [62]

    Designing a QEMU plugin to profile multicore long vector RISC-V architectures: RAVE

    Mulone,A.,Medić,D.,Colonnelli,I.,Aldinucci,M.,2025. Aformal framework for fault tolerance in hybrid scientific workflows. Future Generation Computer Systems 176, 108188. doi:10.1016/j.future. 2025.108188

  60. [63]

    Quantum computing in artificial intelligence:Areviewofquantummachinelearningalgorithms

    Olaitan, O.F., Ayeni, S.O., Olosunde, A., Okeke, F.C., Okonkwo, U.U., Ochieze, C.G., et al., 2025. Quantum computing in artificial intelligence:Areviewofquantummachinelearningalgorithms. Path of Science 11, 7001–7009

  61. [64]

    Simulating large quantum circuits on a small quantum computer

    Peng, T., Harrow, A.W., Ozols, M., Wu, X., 2020. Simulating large quantum circuits on a small quantum computer. Physical review letters 125, 150504

  62. [65]

    Pornmaneerattanatri, S., Tsuji, M., Maheshwari, K., Sato, M., 2026. Python-based workflow system for quantum-hpc hybrid application on hpc system and quantum computer with shared network, in: Pro- ceedings of the Supercomputing Asia and International Conference on High Performance Computing in Asia Pacific Region Workshops, pp. 428–432

  63. [66]

    Prabhakaran, S., Neumann, M., Rinke, S., Wolf, F., Gupta, A., Kale, L.V., 2015. A Batch System with Efficient Adaptive Scheduling for Malleable and Evolving Applications, in: Proceedings of the 2015 IEEE International Parallel and Distributed Processing Symposium, IEEEComputerSociety,USA.pp.429–438. doi:10.1109/IPDPS.2015. 34

  64. [67]

    Dynamic solutions for hybrid quantum-hpc resource allocation,in:2025IEEEInternationalConferenceonQuantumCom- puting and Engineering (QCE), pp

    Rocco, R., Rizzo, S., Barbieri, M., Bettonte, G., Boella, E., Ganz, F., et al., 2025. Dynamic solutions for hybrid quantum-hpc resource allocation,in:2025IEEEInternationalConferenceonQuantumCom- puting and Engineering (QCE), pp. 34–40. doi:10.1109/QCE65121. 2025.10289

  65. [68]

    Bringing quan- tum acceleration to supercomputers

    Ruefenacht, M., Taketani, B.G., et al., 2022. Bringing quan- tum acceleration to supercomputers. IQM/LRZ Technical Report, https://www.quantum.lrz.de/fileadmin/QIC/Downloads/IQMHPC- QC-Integration-White paper. pdf

  66. [69]

    Sarood, O., Langer, A., Gupta, A., Kale, L., 2014. Maximizing throughput of overprovisioned HPC data centers under a strict power budget, in: Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis, IEEE Press, New Orleans, Louisana. pp. 807–818. doi:10.1109/SC.2014.71

  67. [70]

    A Conceptual Architecture for a Quantum-HPC Middleware doi:10.1109/QSW59989.2023.00023, arXiv:2308.06608

    Saurabh, N., Jha, S., Luckow, A., 2023a. A Conceptual Architecture for a Quantum-HPC Middleware doi:10.1109/QSW59989.2023.00023, arXiv:2308.06608

  68. [71]

    A Conceptual Architecture for a Quantum-HPC Middleware.arXiv:2308.06608

    Saurabh, N., Jha, S., Luckow, A., 2023b. A Conceptual Architecture for a Quantum-HPC Middleware.arXiv:2308.06608

  69. [73]

    Accelerating HPC With Quantum Computing: It Is a Software Challenge Too

    Schulz, M., Ruefenacht, M., et al., 2022b. Accelerating HPC With Quantum Computing: It Is a Software Challenge Too. Computing in Science & Engineering 24, 60–64. doi:10.1109/MCSE.2022.3221845

  70. [74]

    A clustering aggregation algorithm on neutral-atoms and annealing quantum processors

    Scotti, R., Bettonte, G., Costantini, A., Marzella, S., Ottaviani, D., Lodi, S., 2024. A clustering aggregation algorithm on neutral-atoms and annealing quantum processors. URL:https://arxiv.org/abs/ 2412.07558,arXiv:2412.07558

  71. [75]

    Referencearchitectureofaquantum-centric supercomputer.arXiv preprint arXiv:2603.10970(2026)

    Seelam, S., Chow, J.M., Córcoles, A., Sheldon, S., Mittal, T., Kandala, A., et al., 2026. Reference architecture of a quantum- centric supercomputer. URL:https://arxiv.org/abs/2603.10970, arXiv:2603.10970

  72. [76]

    Shang, H., Shen, L., Fan, Y., Xu, Z., Guo, C., Liu, J., et al., 2022. Large-scalesimulationofquantumcomputationalchemistryonanew sunway supercomputer, in: SC22: International Conference for High Performance Computing, Networking, Storage and Analysis, IEEE. pp. 1–14

  73. [77]

    Building a software stack for quantum-hpc integration

    Shehata, A., Groszkowski, P., Naughton, T., Meena, M.G., Wong, E., Claudino, D., et al., 2025. Building a software stack for quantum-hpc integration. URL:https://arxiv.org/abs/2503.01787, arXiv:2503.01787

  74. [78]

    ReSHAPE: A Framework for Dynamic Resizing and Scheduling of Homogeneous Applications in aParallelEnvironment,in:2007InternationalConferenceonParallel Processing (ICPP 2007), pp

    Sudarsan, R., Ribbens, C.J., 2007. ReSHAPE: A Framework for Dynamic Resizing and Scheduling of Homogeneous Applications in aParallelEnvironment,in:2007InternationalConferenceonParallel Processing (ICPP 2007), pp. 44–44. doi:10.1109/ICPP.2007.73

  75. [79]

    Sudarsan, R., Ribbens, C.J., Farkas, D., 2009. Dynamic Resizing of Parallel Scientific Simulations: A Case Study Using LAMMPS, in: Proceedings of the 9th International Conference on Computational Science: Part I, Springer-Verlag, Berlin, Heidelberg. pp. 175–184. doi:10.1007/978-3-642-01970-8_18

  76. [80]

    A terminology forscientificworkflowsystems.FutureGenerationComputerSystems 174, 107974

    Suter, F., Coleman, T., Altintas, I., Badia, R.M., Balis, B., Chard, K.,Colonnelli,I.,Deelman,E.,Tommaso,P.D.,Fahringer,T.,Goble, C.A., Jha, S., Katz, D.S., Köster, J., Leser, U., Mehta, K., Oliver, H., Peterson,J.L.,Pizzi,G.,Pottier,L.,Sirvent,R.,Suchyta,E.,Thain,D., Wilkinson, S.R., Wozniak, J.M., da Silva, R.F., 2026. A terminology forscientificworkflo...

  77. [81]

    TowardsaeuropeanHPC/AIecosystem: a community-driven report

    Taborsky, P., Colonnelli, I., Kurowski, K., Sarma, R., Pontoppidan, N.H.,Jansík,B.,etal.,2025. TowardsaeuropeanHPC/AIecosystem: a community-driven report. Procedia Computer Science 255, 140–

  78. [82]

    doi:10.1016/j.procs.2025.02.269

  79. [83]

    Malleability in Modern HPC Sys- tems: Current Experiences, Challenges, and Future Opportuni- ties

    Tarraf, A., Schreiber, M., Cascajo, A., Besnard, J.B., Vef, M.A., Huber, D., et al., 2024. Malleability in Modern HPC Sys- tems: Current Experiences, Challenges, and Future Opportuni- ties. IEEE Transactions on Parallel and Distributed Systems , 1–14URL:https://ieeexplore.ieee.org/document/10541114, doi:10. 1109/TPDS.2024.3406764.conferenceName:IEEETransa...

  80. [84]

    Kubernetes-orchestrated hybrid quantum-classical workflows

    Tejedor, M., Grossi, M., Tüysüz, C., Rocha, R., Vallecorsa, S., 2026. Kubernetes-orchestrated hybrid quantum-classical workflows. URL: https://arxiv.org/abs/2603.24206,arXiv:2603.24206

Showing first 80 references.