pith. sign in
Pith Number

pith:5VY2UBOJ

pith:2018:5VY2UBOJHCOJM2NWSTLERY7HUY
not attested not anchored not stored refs pending

Combining Alchemical Transformation with Physical Pathway to Accurately Compute Absolute Binding Free Energy

Emilio Gallicchio, Lauren Wickstrom, Nanjie Deng

arxiv:1808.09104 v1 · 2018-08-28 · q-bio.BM

Add to your LaTeX paper
\usepackage{pith}
\pithnumber{5VY2UBOJHCOJM2NWSTLERY7HUY}

Prints a linked badge after your title and injects PDF metadata. Compiles on arXiv. Learn more · Embed verified badge

Record completeness

1 Bitcoin timestamp
2 Internet Archive
3 Author claim open · sign in to claim
4 Citations open
5 Replications open
Portable graph bundle live · download bundle · merged state
The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.
Receipt and verification
First computed 2026-05-18T00:07:04.492150Z
Builder pith-number-builder-2026-05-17-v1
Signature Pith Ed25519 (pith-v1-2026-05) · public key
Schema pith-number/v1.0

Canonical hash

ed71aa05c9389c9669b694d648e3e7a61a7bac7c36045a71ca3b3b4205ad7ca0

Aliases

arxiv: 1808.09104 · arxiv_version: 1808.09104v1 · doi: 10.48550/arxiv.1808.09104 · pith_short_12: 5VY2UBOJHCOJ · pith_short_16: 5VY2UBOJHCOJM2NW · pith_short_8: 5VY2UBOJ
Agent API
Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/5VY2UBOJHCOJM2NWSTLERY7HUY \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: ed71aa05c9389c9669b694d648e3e7a61a7bac7c36045a71ca3b3b4205ad7ca0
Canonical record JSON
{
  "metadata": {
    "abstract_canon_sha256": "9cb85ae84590af1f04c440f93ac77e7802fdb86dbdd4f6e71249c2eca4946210",
    "cross_cats_sorted": [],
    "license": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
    "primary_cat": "q-bio.BM",
    "submitted_at": "2018-08-28T03:44:51Z",
    "title_canon_sha256": "4558774ff6ef27e7ad930bf5ca54e8796e4d64e33d7771c924c31e5a63bb695c"
  },
  "schema_version": "1.0",
  "source": {
    "id": "1808.09104",
    "kind": "arxiv",
    "version": 1
  }
}