ConTact introduces a contact-then-act architecture with distance-biased cross-attention and contact-weighted loss for antibody CDR design, reporting 5-6% better backbone RMSD and superior contact metrics on CHIMERA-Bench splits.
arXiv preprint arXiv:2509.15796 , year=
5 Pith papers cite this work. Polarity classification is still indexing.
5
Pith papers citing it
years
2026 5verdicts
UNVERDICTED 5representative citing papers
AgForce improves antigen-conditioned antibody design by using framework dropout, gated bottlenecks, hyperbolic cross attention, MDN sequence head with Potts-like coupling, annealed MCL, and antigen cycle consistency to achieve 8% better amino acid recovery and superior binding metrics on CHIMERA-BEN
EvoStruct integrates evolutionary priors from a protein language model with structural priors from an E(3)-equivariant GNN to raise amino acid recovery by 16% and diversity by 2.3x on CHIMERA-Bench while cutting perplexity 43%.
MP2D is a framework that guides discrete diffusion denoising with constrained MCTS and Pareto rewards to optimize protein sequences for four to five simultaneous objectives, outperforming baselines on antimicrobial peptide and binder design tasks.
Protein Thoughts uses hypothesis-guided entropy-regularized Tree-of-Thoughts search and embedding flow matching to achieve mean best-binder rank 11.2 and 91.08 Micro-F1 on SHS148k by keeping sequence, structure, interface, and chemical signals transparent.
citing papers explorer
-
ConTact: Contact-First Antibody CDR Design via Explicit Interface Reasoning
ConTact introduces a contact-then-act architecture with distance-biased cross-attention and contact-weighted loss for antibody CDR design, reporting 5-6% better backbone RMSD and superior contact metrics on CHIMERA-Bench splits.
-
AgForce Enables Antigen-conditioned Generative Antibody Design
AgForce improves antigen-conditioned antibody design by using framework dropout, gated bottlenecks, hyperbolic cross attention, MDN sequence head with Potts-like coupling, annealed MCL, and antigen cycle consistency to achieve 8% better amino acid recovery and superior binding metrics on CHIMERA-BEN
-
EvoStruct: Bridging Evolutionary and Structural Priors for Antibody CDR Design via Protein Language Model Adaptation
EvoStruct integrates evolutionary priors from a protein language model with structural priors from an E(3)-equivariant GNN to raise amino acid recovery by 16% and diversity by 2.3x on CHIMERA-Bench while cutting perplexity 43%.
-
MP2D: Constrained Monte Carlo Tree-Guided Diffusion for Multi-Objective Protein Sequence Design
MP2D is a framework that guides discrete diffusion denoising with constrained MCTS and Pareto rewards to optimize protein sequences for four to five simultaneous objectives, outperforming baselines on antimicrobial peptide and binder design tasks.
-
Protein Thoughts: Interpretable Reasoning with Tree of Thoughts and Embedding-Space Flow Matching for Protein-Protein Interaction Discovery
Protein Thoughts uses hypothesis-guided entropy-regularized Tree-of-Thoughts search and embedding flow matching to achieve mean best-binder rank 11.2 and 91.08 Micro-F1 on SHS148k by keeping sequence, structure, interface, and chemical signals transparent.