Chem2Gen-Bench is a new benchmark and evaluation framework for measuring alignment between chemical and genetic perturbation responses in matched cell-target contexts using retrieval, similarity, and embedding comparisons.
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OCOO-T is a flow-matching Transformer model that directly denoises continuous gene expression profiles to predict transcriptional responses to perturbations and reports state-of-the-art results on Tahoe100M, Replogle, and PBMC benchmarks.
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Chem2Gen-Bench: Benchmarking Chemical-to-Genetic Translation in Perturbation Response Space
Chem2Gen-Bench is a new benchmark and evaluation framework for measuring alignment between chemical and genetic perturbation responses in matched cell-target contexts using retrieval, similarity, and embedding comparisons.
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OCOO-T : A Simple and Scalable Virtual Cell Model for Transcriptional Perturbation Response Prediction
OCOO-T is a flow-matching Transformer model that directly denoises continuous gene expression profiles to predict transcriptional responses to perturbations and reports state-of-the-art results on Tahoe100M, Replogle, and PBMC benchmarks.