Backdoor-adjusted ATEs on 21,098 UK Biobank participants showed total femur BMC and BMD with the largest hip fracture risk reductions (-0.0047 per SD), and adding the top 11 phenotypes to clinical variables raised AUC to 0.842 versus FRAX 0.709.
Causal Inference About the Effects of Interventions From Observational Studies in Medical Journals
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DXA-Derived Skeletal Phenotypes and Hip Fracture Risk: A Backdoor-Adjusted Causal Analysis
Backdoor-adjusted ATEs on 21,098 UK Biobank participants showed total femur BMC and BMD with the largest hip fracture risk reductions (-0.0047 per SD), and adding the top 11 phenotypes to clinical variables raised AUC to 0.842 versus FRAX 0.709.