KG-TRACE fuses genomic features with RotatE KG embeddings via an epistemic trust gate for AMR prediction, reporting 0.976 AUROC on isoniazid resistance in the CRyPTIC cohort plus 92.5% symbolic coverage via a new Biological Grounding Ratio metric.
Interpretable genotype-to- phenotype classifiers with performance guarantees,
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KG-TRACE: A Neuro-Symbolic Framework for Mechanistic Grounding in Antimicrobial Resistance Prediction
KG-TRACE fuses genomic features with RotatE KG embeddings via an epistemic trust gate for AMR prediction, reporting 0.976 AUROC on isoniazid resistance in the CRyPTIC cohort plus 92.5% symbolic coverage via a new Biological Grounding Ratio metric.