Vertex function-based filtrations reproduce known Betti-2 structures and essential genes from Vietoris-Rips while enabling previously infeasible Betti-3 analysis and identifying new driver genes in cancer networks.
Applications of topological data analysis in oncology
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Scalable vertex guided filtrations identify structurally relevant genes in cancer networks
Vertex function-based filtrations reproduce known Betti-2 structures and essential genes from Vietoris-Rips while enabling previously infeasible Betti-3 analysis and identifying new driver genes in cancer networks.