A B-spline parameterized ICTMC model called the spline clock recovers true time-varying rates more accurately in simulations than competitors and detects time-variation in foamy virus and SARS-CoV-2 data.
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Smoothly Time-Varying Continuous Time Markov Chains in Phylogenetics
A B-spline parameterized ICTMC model called the spline clock recovers true time-varying rates more accurately in simulations than competitors and detects time-variation in foamy virus and SARS-CoV-2 data.