A new tree-conditioned edit-flow model for ancestral sequence reconstruction achieves reasonable accuracy on substitution-only evolved sequences and superior localization of changes on natural indel-rich sequences.
PAML 4: Phylogenetic analysis by maximum likelihood.Molecular Biology and Evolution, 24(8):1586–1591
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Tree-Conditioned Edit Flows for Ancestral Sequence Reconstruction
A new tree-conditioned edit-flow model for ancestral sequence reconstruction achieves reasonable accuracy on substitution-only evolved sequences and superior localization of changes on natural indel-rich sequences.