The paper reviews lumen formation by viewing lumens as active balloons whose growth and maintenance are driven by out-of-equilibrium physical processes in cell layers.
While significant experimental and theoretical progress has been made, several open questions remain that we believe are particularly well-suited for physics-based approaches
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Lumens as active balloons: a biological physics review
The paper reviews lumen formation by viewing lumens as active balloons whose growth and maintenance are driven by out-of-equilibrium physical processes in cell layers.