Vertex function-based filtrations reproduce known Betti-2 structures and essential genes from Vietoris-Rips while enabling previously infeasible Betti-3 analysis and identifying new driver genes in cancer networks.
Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma
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Scalable vertex guided filtrations identify structurally relevant genes in cancer networks
Vertex function-based filtrations reproduce known Betti-2 structures and essential genes from Vietoris-Rips while enabling previously infeasible Betti-3 analysis and identifying new driver genes in cancer networks.