New episode-specific estimands and weighting estimators are introduced for master protocol trials allowing re-enrollment, preserving randomized comparisons under standard assumptions.
and Pestana, Roberto Carmagnani and Zabor, Emily C
2 Pith papers cite this work. Polarity classification is still indexing.
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A new Bayesian phase I/II basket trial design (DF-EXNEX) with extended EXNEX mixture priors for robust borrowing across subtrials to select subtrial-specific optimal biological doses, shown in simulations to outperform no-borrowing in most of 70 scenarios.
citing papers explorer
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Evolving Longitudinal Patient Histories and Re-enrollment in Master Protocol Trials
New episode-specific estimands and weighting estimators are introduced for master protocol trials allowing re-enrollment, preserving randomized comparisons under standard assumptions.
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A Bayesian Phase I/II basket design with robust information borrowing to identify subtrial-specific optimal biological doses
A new Bayesian phase I/II basket trial design (DF-EXNEX) with extended EXNEX mixture priors for robust borrowing across subtrials to select subtrial-specific optimal biological doses, shown in simulations to outperform no-borrowing in most of 70 scenarios.