PLM embeddings improve antibody monomer CDR-H3 accuracy but fail on complexes without co-evolution signals, while MSA refinement and convergence-aware recycling yield gains over AlphaFold3 on held-out antibody-antigen data without retraining.
Class switch recombination and hypermuta- tion require activation-induced cytidine deaminase (aid), a potential rna editing enzyme.Cell, 102(5):553–563, sep 2000
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.QM 1years
2026 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
Computational Modeling of Antibody-Antigen Complexes: PLM-Based and MSA-Based Approaches
PLM embeddings improve antibody monomer CDR-H3 accuracy but fail on complexes without co-evolution signals, while MSA refinement and convergence-aware recycling yield gains over AlphaFold3 on held-out antibody-antigen data without retraining.