ProtDBench standardizes protein binder design evaluation using wet-lab data, exposing verifier biases, metric dependencies, and trade-offs between success rate, speed, and structural diversity.
URL https://www.biorxiv.org/content/ early/2025/08/16/2025.08.15.670450
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ProtDBench: A Unified Benchmark of Protein Binder Design and Evaluation
ProtDBench standardizes protein binder design evaluation using wet-lab data, exposing verifier biases, metric dependencies, and trade-offs between success rate, speed, and structural diversity.