GoForth is a forward-trained encoder-decoder RNA language model that generates sequences under mixed constraints on fold, sequence, and coding by separating sequence prior, forward folding sampler, and reward oracle.
Joint Design of 5' Untranslated Region and Coding Sequence of
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GoForth: Language Models for RNA Design under Structure, Sequence, and Coding Constraints
GoForth is a forward-trained encoder-decoder RNA language model that generates sequences under mixed constraints on fold, sequence, and coding by separating sequence prior, forward folding sampler, and reward oracle.