Integrating missed-event correction into Bayesian modeling of IP3R gating clarifies that Park and Drive modes are both 3-state Markov chains with mode-specific kinetics, and intermediate Ca2+ strongly suppresses Drive-to-Park transitions.
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Accounting for Missed Events in the Bayesian Modeling of IP3R Multimodal Gating
Integrating missed-event correction into Bayesian modeling of IP3R gating clarifies that Park and Drive modes are both 3-state Markov chains with mode-specific kinetics, and intermediate Ca2+ strongly suppresses Drive-to-Park transitions.