Inverse Geometric Approach to the Simulation of the Circular Growth. The Case of Multicellular Tumor Spheroids

We demonstrate the power of the genetic algorithms to construct the cellular automata model simulating the growth of 2-dimensional close-to-circular clusters revealing the desired properties, such as the growth rate and, at the same time, the fractal behavior of their contours. The possible application of the approach in the field of tumor modeling is outlined.