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arxiv: 1305.0490 · v1 · pith:VSVZFQFZnew · submitted 2013-05-02 · 🧬 q-bio.NC

An experimental evidence-based computational paradigm for new logic-gates in neuronal activity

classification 🧬 q-bio.NC
keywords activityexperimentallogic-gatesnetworkneuronalparadigmstimulationsbiological
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We propose a new experimentally corroborated paradigm in which the functionality of the brain's logic-gates depends on the history of their activity, e.g. an OR-gate that turns into a XOR-gate over time. Our results are based on an experimental procedure where conditioned stimulations were enforced on circuits of neurons embedded within a large-scale network of cortical cells in-vitro. The underlying biological mechanism is the unavoidable increase of neuronal response latency to ongoing stimulations, which imposes a non-uniform gradual stretching of network delays.

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