Recognition: unknown
DMDSC: A Dynamic-Margin Deep Simplex Classifier for Open-Set Recognition on Medical Image Datasets
Pith reviewed 2026-05-09 19:43 UTC · model grok-4.3
The pith
Dynamic margins based on label frequency improve open-set recognition for rare medical conditions.
A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.
Core claim
The DMDSC framework features a dynamic margin approach that automatically adapts class-specific margins based on label frequency. This enforces a higher penalty and tighter feature clustering for rare pathologies to counteract the effects of data imbalance in open-set recognition on medical image datasets. Experiments on BloodMNIST, OCTMNIST, DermaMNIST, and BreaKHis show it outperforms state-of-the-art methods.
What carries the argument
The dynamic margin scaled according to label frequency within the Deep Simplex Classifier structure, which uses Neural Collapse to maximize inter-class separation but now with class-dependent margins.
If this is right
- The model achieves superior performance on open-set recognition tasks across multiple medical imaging benchmarks with class imbalance.
- Rare pathologies receive tighter feature clustering due to increased margin penalties.
- Known class classification accuracy is maintained while improving rejection of unknown samples.
Where Pith is reading between the lines
- This approach of frequency-dependent margins could be tested in non-medical domains with similar imbalance issues.
- Integrating it with uncertainty-aware variants of the simplex classifier might yield additional gains in clinical applications.
Load-bearing premise
Scaling the margin by label frequency alone will produce tighter and more separable clusters for rare classes without introducing overfitting to the frequency statistics or reducing performance on common classes.
What would settle it
Training the DMDSC model and a fixed-margin baseline on a medical dataset like BloodMNIST, then checking if rare class features show reduced variance and if unknown sample rejection rates increase without harming common class accuracy.
Figures
read the original abstract
Medical imaging datasets are often characterized by extreme class imbalances, where rare pathologies are significantly underrepresented compared to common conditions. This imbalance poses a dual challenge for Open-Set Recognition (OSR): models must maintain high classification accuracy on known classes while reliably rejecting unknown samples unseen during training in the clinical settings. While recently proposed Deep Simplex Classifier (DSC)~\cite{cevikalp2024reaching} and UnCertainty-aware Deep Simplex Classifier (UCDSC)~\cite{Aditya_2026_WACV} successfully leverage Neural Collapse to ensure maximal inter-class separation, they rely on a uniform margin that does not account for the varying densities of medical classes. In this paper, we propose DMDSC an enhanced framework featuring a dynamic margin approach. Our approach automatically adapts class-specific margins based on label frequency, enforcing a higher penalty and tighter feature clustering for rare pathologies to counteract the effects of data imbalance. Extensive experiments conducted on diverse medical benchmarks on BloodMNIST\cite{medmnistv2}, OCTMNIST\cite{medmnistv2}, DermaMNIST\cite{medmnistv2}, and BreaKHis~\cite{spanhol2015dataset} datasets, demonstrate that our framework outperforms state-of-the-art methods.
Editorial analysis
A structured set of objections, weighed in public.
Referee Report
Summary. The paper proposes DMDSC, an extension of the Deep Simplex Classifier (DSC) framework that introduces class-specific dynamic margins scaled by label frequency to better handle extreme class imbalance in open-set recognition for medical images. It claims this enforces tighter feature clustering for rare pathologies and yields superior performance over prior DSC/UCDSC variants and other SOTA methods on the BloodMNIST, OCTMNIST, DermaMNIST, and BreaKHis benchmarks.
Significance. If the empirical gains hold under rigorous validation, the dynamic-margin idea offers a lightweight, frequency-aware modification to Neural-Collapse-based classifiers that could improve rare-class detection and unknown rejection in clinically imbalanced settings without requiring architectural changes.
major comments (2)
- [Method] The central justification—that scaling the simplex margin inversely with label frequency produces measurably tighter within-class collapse for rare classes while preserving the Neural-Collapse fixed point—lacks any derivation, fixed-point analysis, or gradient-magnitude study. No section shows that the non-uniform margin schedule keeps the attractive fixed point intact or avoids destabilizing optimization for high-frequency classes.
- [Experiments] The abstract asserts outperformance on four datasets, yet the provided text supplies neither quantitative tables, ablation results isolating the dynamic-margin component, nor statistical tests. Without these, the load-bearing empirical claim cannot be assessed.
minor comments (1)
- [Abstract] The abstract states 'extensive experiments' but reports no key metrics, which reduces its utility as a standalone summary.
Simulated Author's Rebuttal
We thank the referee for the detailed and constructive review. The comments highlight important areas for strengthening the theoretical justification and empirical presentation. We address each major comment point by point below and will revise the manuscript accordingly.
read point-by-point responses
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Referee: [Method] The central justification—that scaling the simplex margin inversely with label frequency produces measurably tighter within-class collapse for rare classes while preserving the Neural-Collapse fixed point—lacks any derivation, fixed-point analysis, or gradient-magnitude study. No section shows that the non-uniform margin schedule keeps the attractive fixed point intact or avoids destabilizing optimization for high-frequency classes.
Authors: We agree that the submitted manuscript lacks an explicit derivation and fixed-point analysis for the dynamic-margin schedule. In the revision we will add a dedicated subsection deriving the modified Neural Collapse objective under class-specific margins. The analysis will show that the frequency-scaled margin preserves the attractive fixed point by scaling the within-class variance term proportionally to inverse frequency, while the inter-class separation term remains unchanged. We will also include a gradient-magnitude study demonstrating that the schedule does not destabilize optimization for high-frequency classes, as their gradients remain bounded by the original uniform-margin case. revision: yes
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Referee: [Experiments] The abstract asserts outperformance on four datasets, yet the provided text supplies neither quantitative tables, ablation results isolating the dynamic-margin component, nor statistical tests. Without these, the load-bearing empirical claim cannot be assessed.
Authors: We acknowledge that the quantitative tables, ablation studies isolating the dynamic margin, and statistical tests were insufficiently detailed or formatted in the submitted version. The revision will prominently include full performance tables for BloodMNIST, OCTMNIST, DermaMNIST, and BreaKHis, with direct comparisons to DSC, UCDSC, and other SOTA baselines. We will add a dedicated ablation subsection varying only the margin schedule (uniform vs. dynamic) while keeping all other components fixed, and report paired statistical tests (e.g., McNemar or t-tests with p-values) across multiple runs to support the outperformance claims. revision: yes
Circularity Check
Dynamic margin extension on prior DSC relies on self-citation for Neural Collapse but adds independent frequency-based rule
full rationale
The manuscript builds DMDSC directly on DSC (cevikalp2024reaching) and UCDSC (Aditya_2026_WACV) to leverage Neural Collapse for simplex separation, then introduces a new dynamic margin scaled by label frequency. One citation (UCDSC) has author overlap, qualifying as minor self-citation, but it is not load-bearing for the central novelty: the frequency-driven margin adaptation itself is presented as an explicit design choice without any equation that reduces the claimed tighter clustering or OSR gain to a fitted parameter or self-defined quantity. No derivation chain collapses by construction; the paper remains self-contained against external benchmarks.
Axiom & Free-Parameter Ledger
Reference graph
Works this paper leans on
-
[1]
Mendeley Data, V1 (2020).https://doi.org/10
Acevedo, A., Merino, A., Alférez, S., Cabrera, J.R., Pereira, C., León, A., Sánchez, P.: A dataset for microscopic peripheral blood cell images for development of au- tomatic recognition systems. Mendeley Data, V1 (2020).https://doi.org/10. 17632/snkd93bnjr.1,https://doi.org/10.17632/snkd93bnjr.1
-
[2]
Data in Brief30, 105474 (2020).https://doi.org/ 10.1016/j.dib.2020.105474
Acevedo, A., Merino, A., Alférez, S., Cabrera, J.R., Pereira, C., León, A., Sánchez, P.: A dataset of microscopic peripheral blood cell images for development of au- tomatic recognition systems. Data in Brief30, 105474 (2020).https://doi.org/ 10.1016/j.dib.2020.105474
-
[3]
In: Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision (WACV)
Aditya, A., Kumar, N., Shigwan, S.: UCDSC: Open set uncertainty aware deep simplex classifier for medical image datasets. In: Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision (WACV). pp. 4787–4796 (March 2026)
2026
-
[4]
Bendale, A., Boult, T.E.: Towards open world recognition. CVPR pp. 1893–1902 (2015)
1902
-
[5]
IEEE Transactions on Neural Networks and Learning Systems36(5), 8178–8191 (2024)
Cevikalp, H., Saribas, H., Uzun, B.: Reaching nirvana: Maximizing the margin in both euclidean and angular spaces for deep neural network classification. IEEE Transactions on Neural Networks and Learning Systems36(5), 8178–8191 (2024)
2024
-
[6]
Pattern Recognition138, 109385 (2023)
Cevikalp, H., Uzun, B., Salk, Y., Saribas, H., Köpüklü, O.: From anomaly detection to open set recognition: Bridging the gap. Pattern Recognition138, 109385 (2023)
2023
-
[7]
IEEE Transactions on Pattern Analysis and Machine Intelligence44(11), 8065–8081 (2021)
Chen, G., Peng, P., Wang, X., Tian, Y.: Adversarial reciprocal points learning for open set recognition. IEEE Transactions on Pattern Analysis and Machine Intelligence44(11), 8065–8081 (2021)
2021
-
[8]
In: European conference on computer vision
Chen, G., Qiao, L., Shi, Y., Peng, P., Li, J., Huang, T., Pu, S., Tian, Y.: Learning open set network with discriminative reciprocal points. In: European conference on computer vision. pp. 507–522. Springer (2020)
2020
-
[9]
Chin, T.J., Cai, Z., Neumann, F.: Robust fitting in computer vision: Easy or hard? In: Proceedings of the European Conference on Computer Vision (ECCV). pp. 701–716 (2018)
2018
-
[10]
Codella, N., Rotemberg, V., Tschandl, P., Celebi, M.E., Dusza, S., Gutman, D., Helba,B.,Kalloo,A.,Liopyris,K.,Marchetti,M.,etal.:Skinlesionanalysistoward melanoma detection 2018: A challenge hosted by the international skin imaging collaboration (isic). arXiv preprint arXiv:1902.03368 (2019)
work page Pith review arXiv 2018
-
[11]
Ad- vances in Neural Information Processing Systems31(2018)
Dhamija, A.R., Günther, M., Boult, T.: Reducing network agnostophobia. Ad- vances in Neural Information Processing Systems31(2018)
2018
-
[12]
In: British Machine Vision Conference
Ge, Z., Demyanov, S., Chen, Z., Garnavi, R.: Generative openmax for multi-class open set classification. In: British Machine Vision Conference. BMVA Press (2017)
2017
-
[13]
IEEE TPAMI43(10), 3614–3631 (2021)
Geng, C., Huang, S.J., Chen, S.: Recent advances in open set recognition: A survey. IEEE TPAMI43(10), 3614–3631 (2021)
2021
-
[14]
IEEE transactions on pattern analysis and machine intelligence43(10), 3614–3631 (2020)
Geng, C., Huang, S.j., Chen, S.: Recent advances in open set recognition: A survey. IEEE transactions on pattern analysis and machine intelligence43(10), 3614–3631 (2020)
2020
-
[15]
He,K.,Zhang,X.,Ren,S.,Sun,J.:Deepresiduallearningforimagerecognition.In: Proceedings of the IEEE conference on computer vision and pattern recognition. pp. 770–778 (2016)
2016
-
[16]
Deep Anomaly Detection with Outlier Exposure
Hendrycks, D., Mazeika, M., Dietterich, T.: Deep anomaly detection with outlier exposure. arXiv preprint arXiv:1812.04606 (2018)
work page Pith review arXiv 2018
-
[17]
In: Proceedings of the 7th International Conference on Learning Repre- sentations (ICLR) (2019),https://openreview.net/forum?id=HyxCxhRcY7 16 Vishal et al
Hendrycks, D., Mazeika, M., Dietterich, T.: Deep anomaly detection with outlier exposure. In: Proceedings of the 7th International Conference on Learning Repre- sentations (ICLR) (2019),https://openreview.net/forum?id=HyxCxhRcY7 16 Vishal et al
2019
-
[18]
Intelligent data analysis6(5), 429–449 (2002)
Japkowicz, N., Stephen, S.: The class imbalance problem: A systematic study. Intelligent data analysis6(5), 429–449 (2002)
2002
-
[19]
Cell172(5), 1122– 1131.e9 (2018).https://doi.org/10.1016/j.cell.2018.02.010
Kermany, D.S., Goldbaum, M., Cai, W., Valentim, C.C., Liang, H., Baxter, S.L., McKeown, A., Yang, G., Wu, X., Yan, F., Dong, J., et al.: Identifying medical diagnoses and treatable diseases by image-based deep learning. Cell172(5), 1122– 1131.e9 (2018).https://doi.org/10.1016/j.cell.2018.02.010
-
[20]
Scientific Reports15(1), 22617 (2025)
Lin, Y., He, S., Luo, W.: Dynamic margin contrastive learning for open-set recog- nition in long-tailed sonar imagery. Scientific Reports15(1), 22617 (2025)
2025
-
[21]
In: International conference on medical image computing and computer-assisted intervention
Liu, M., Xu, L., Zhang, J.: Learning large margin sparse embeddings for open set medical diagnosis. In: International conference on medical image computing and computer-assisted intervention. pp. 548–558. Springer (2023)
2023
-
[22]
In: Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision
Miller, D., Sunderhauf, N., Milford, M., Dayoub, F.: Class anchor clustering: A loss for distance-based open set recognition. In: Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision. pp. 3570–3578 (2021)
2021
-
[23]
In: European conference on computer vision
Moon, W., Park, J., Seong, H.S., Cho, C.H., Heo, J.P.: Difficulty-aware simulator for open set recognition. In: European conference on computer vision. pp. 365–381. Springer (2022)
2022
-
[24]
Kaggle (2023),https:// www.kaggle.com/datasets/syedalinaqvi/augmented-skin-conditions-image- dataset
Naqvi, S.A.R.: Augmented skin conditions image dataset. Kaggle (2023),https:// www.kaggle.com/datasets/syedalinaqvi/augmented-skin-conditions-image- dataset
2023
-
[25]
In: ECCV
Neal, L., et al.: Open set recognition with counterfactual images. In: ECCV. pp. 613–628 (2018)
2018
-
[26]
In: Proceedings of the IEEE/CVF conference on computer vision and pattern recognition
Oza, P., Patel, V.M.: C2ae: Class conditioned auto-encoder for open-set recogni- tion. In: Proceedings of the IEEE/CVF conference on computer vision and pattern recognition. pp. 2307–2316 (2019)
2019
-
[27]
Proceedings of the National Academy of Sciences117(40), 24652–24663 (2020)
Papyan, V., Han, X., Donoho, D.L.: Prevalence of neural collapse during the ter- minal phase of deep learning training. Proceedings of the National Academy of Sciences117(40), 24652–24663 (2020)
2020
-
[28]
IEEE Transactions on Pattern Analysis and Machine Intelligence40(3), 762–768 (2018)
Rudd, E.M., et al.: The extreme value machine. IEEE Transactions on Pattern Analysis and Machine Intelligence40(3), 762–768 (2018)
2018
-
[29]
IEEE TPAMI36(11), 2317–2324 (2014)
Scheirer, W.J., Jain, L.P., Boult, T.E.: Probability models for open set recognition. IEEE TPAMI36(11), 2317–2324 (2014)
2014
-
[30]
IEEE transactions on pattern analysis and machine intelligence35(7), 1757–1772 (2012)
Scheirer, W.J., de Rezende Rocha, A., Sapkota, A., Boult, T.E.: Toward open set recognition. IEEE transactions on pattern analysis and machine intelligence35(7), 1757–1772 (2012)
2012
-
[31]
Ieee transactions on biomedical engineering 63(7), 1455–1462 (2015)
Spanhol, F.A., Oliveira, L.S., Petitjean, C., Heutte, L.: A dataset for breast cancer histopathological image classification. Ieee transactions on biomedical engineering 63(7), 1455–1462 (2015)
2015
-
[32]
IEEE transactions on pattern analysis and machine intelligence30(11), 1958–1970 (2008)
Torralba, A., Fergus, R., Freeman, W.T.: 80 million tiny images: A large data set for nonparametric object and scene recognition. IEEE transactions on pattern analysis and machine intelligence30(11), 1958–1970 (2008)
1958
-
[33]
Scientific data5(1), 180161 (2018)
Tschandl, P., Rosendahl, C., Kittler, H.: The ham10000 dataset, a large collection of multi-source dermatoscopic images of common pigmented skin lesions. Scientific data5(1), 180161 (2018)
2018
-
[34]
Pattern Recogni- tion126, 108564 (2022)
Wang, Z., Dong, Q., Guo, W., Li, D., Zhang, J., Du, W.: Geometric imbalanced deep learning with feature scaling and boundary sample mining. Pattern Recogni- tion126, 108564 (2022)
2022
-
[35]
IEEE Access12, 122852–122877 (2024).https://doi.org/10.1109/ACCESS.2024.3442569 DMDSC 17
Xu, Y., Wang, R., Zhao, R.W., Xiao, X., Feng, R.: Semi-supervised and class- imbalanced open set medical image recognition. IEEE Access12, 122852–122877 (2024).https://doi.org/10.1109/ACCESS.2024.3442569 DMDSC 17
-
[36]
In: Proceedings of the IEEE conference on computer vision and pattern recognition
Yang, H.M., Zhang, X.Y., Yin, F., Liu, C.L.: Robust classification with convolu- tional prototype learning. In: Proceedings of the IEEE conference on computer vision and pattern recognition. pp. 3474–3482 (2018)
2018
-
[37]
International Journal of Computer Vision132(12), 5635–5662 (2024)
Yang, J., Zhou, K., Li, Y., Liu, Z.: Generalized out-of-distribution detection: A survey. International Journal of Computer Vision132(12), 5635–5662 (2024)
2024
-
[38]
Scientific Data8(1), 1–14 (2021)
Yang, J., Shi, Y., Ni, B., et al.: Medmnist v2: A large-scale lightweight benchmark for 2d and 3d biomedical image classification. Scientific Data8(1), 1–14 (2021)
2021
-
[39]
In: CVPR
Yoshihashi, R., et al.: Classification-reconstruction learning for open-set recogni- tion. In: CVPR. pp. 4016–4025 (2019)
2019
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