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ProtoSAM: One-Shot Medical Image Segmentation With Foundational Models

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arxiv 2407.07042 v2 pith:7SC6JUD3 submitted 2024-07-09 cs.CV cs.AI

ProtoSAM: One-Shot Medical Image Segmentation With Foundational Models

classification cs.CV cs.AI
keywords imagesegmentationmedicalmodelprotosamfoundationinitialmask
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates an initial coarse segmentation mask using the ALPnet prototypical network, augmented with a DINOv2 encoder. Following the extraction of an initial mask, prompts are extracted, such as points and bounding boxes, which are then input into the Segment Anything Model (SAM). State-of-the-art results are shown on several medical image datasets and demonstrate automated segmentation capabilities using a single image example (one shot) with no need for fine-tuning of the foundation model. Our code is available at: https://github.com/levayz/ProtoSAM

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Forward citations

Cited by 6 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score.

  1. Prototype Memory-Guided Training-Free Anomaly Classification and Localization in Prenatal Ultrasound

    cs.CV 2026-07 unverdicted novelty 7.0

    A training-free prototype memory-guided framework for multi-class prenatal ultrasound anomaly classification and localization using few reference images per class, validated on a 9-category multi-center dataset.

  2. Memory-Supported Synergistic Adaptation for Training-Free Test-Time Medical Image Segmentation

    cs.CV 2026-07 conditional novelty 6.0

    MSSA improves test-time medical image segmentation by storing reliable vision-language predictions in a memory bank and using stored images as prototypes to segment new images, without updating model weights.

  3. Mask to Concept: Auto-Promptable SAM3 via Efficient Test-Time Concept Embedding Search for Few-Shot Annotation

    cs.CV 2026-06 unverdicted novelty 6.0

    M2C turns SAM3 into an auto-promptable annotator for medical few-shot segmentation via test-time concept embedding optimization and uncertainty-driven active refinement.

  4. DiffuSAM: Diffusion-Based Prompt-Free SAM2 for Few-Shot and Source-Free Medical Image Segmentation

    cs.CV 2026-04 unverdicted novelty 6.0

    DiffuSAM synthesizes SAM2-compatible mask embeddings via a diffusion prior conditioned on prior slices to enable accurate prompt-free medical image segmentation under SF-UDA and few-shot settings.

  5. RPG-SAM: Reliability-Weighted Prototypes and Geometric Adaptive Threshold Selection for Training-Free One-Shot Polyp Segmentation

    cs.CV 2026-03 unverdicted novelty 6.0

    RPG-SAM improves one-shot polyp segmentation by weighting high-fidelity support features and dynamically adjusting thresholds via morphological consensus, yielding 5.56% mIoU gain on Kvasir.

  6. Mask to Concept: Auto-Promptable SAM3 via Efficient Test-Time Concept Embedding Search for Few-Shot Annotation

    cs.CV 2026-06 unverdicted novelty 5.0

    M2C performs test-time concept embedding search in frozen SAM3 plus hybrid uncertainty estimation to enable few-shot medical segmentation with active human correction.