In isotropic Gaussian random field fitness landscapes the expected number of local optima is determined by the correlation of fitness effects, with modularity increasing and locus heterogeneity decreasing the count.
Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems , Volume =
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Simple sign epistasis causes evolutionary detours and occurs far more often than reciprocal sign epistasis in weakly epistatic fitness landscapes.
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Epistatic strength, modularity, and locus heterogeneity shape the number of local optima in fitness landscapes
In isotropic Gaussian random field fitness landscapes the expected number of local optima is determined by the correlation of fitness effects, with modularity increasing and locus heterogeneity decreasing the count.
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Simple sign epistasis and evolutionary detours in fitness landscapes
Simple sign epistasis causes evolutionary detours and occurs far more often than reciprocal sign epistasis in weakly epistatic fitness landscapes.