Mean field mutation dynamics and the continuous Luria-Delbr\"uck distribution
classification
🧮 math-ph
math.MPmath.PRq-bio.PE
keywords
distributionluria-delbrcontinuouscorrespondingfieldmeanmutationanalysis
read the original abstract
The Luria-Delbr\"uck mutation model has a long history and has been mathematically formulated in several different ways. Here we tackle the problem in the case of a continuous distribution using some mathematical tools from nonlinear statistical physics. Starting from the classical formulations we derive the corresponding differential models and show that under a suitable mean field scaling they correspond to generalized Fokker-Planck equations for the mutants distribution whose solutions are given by the corresponding Luria-Delbr\"uck distribution. Numerical results confirming the theoretical analysis are also presented.
This paper has not been read by Pith yet.
discussion (0)
Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.