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Measures of hydroxymethylation

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arxiv 1708.04819 v2 pith:4BRONT7S submitted 2017-08-16 q-bio.QM q-bio.GNstat.AP

Alla Slynko , Axel Benner This is my paper · ORCID
classification q-bio.QMq-bio.GNstat.AP
keywords betadatadeltahydroxymethylationmeasurespropertiesrealaddress
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abstract

Hydroxymethylcytosine (5hmC) methylation is known to be a possible epigenetic mark impacting genome stability. In this paper, we address the existing 5hmC measure $\Delta \beta$ and discuss its properties both analytically and empirically on real data. Then we introduce several alternative hydroxymethylation measures and compare their properties with those of $\Delta \beta$. All results will be illustrated by means of real data analyses.

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