LLMs lack temporal awareness of medical knowledge, showing gradual performance decline on up-to-date facts, much lower accuracy on historical knowledge (25-54% relative), and inconsistent year-to-year predictions.
Biomni: A general-purpose biomedical ai agent
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AssayBench is a new gene-ranking benchmark for phenotypic CRISPR screens that shows zero-shot generalist LLMs outperform both biology-specific LLMs and trainable baselines on adjusted nDCG.
DrugSAGE accumulates cross-task memory of skills, statistical evidence, and recurring errors to let LLM agents achieve top-ranked performance on molecular property prediction tasks with reduced or zero test-time search.
Hygieia is a new AI agent system that integrates phenotypes, genetics, and records to achieve superior rare disease diagnosis and gene prioritization with confidence scores.
citing papers explorer
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Large Language Models Lack Temporal Awareness of Medical Knowledge
LLMs lack temporal awareness of medical knowledge, showing gradual performance decline on up-to-date facts, much lower accuracy on historical knowledge (25-54% relative), and inconsistent year-to-year predictions.
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AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents
AssayBench is a new gene-ranking benchmark for phenotypic CRISPR screens that shows zero-shot generalist LLMs outperform both biology-specific LLMs and trainable baselines on adjusted nDCG.
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DrugSAGE:Self-evolving Agent Experience for Efficient State-of-the-Art Drug Discovery
DrugSAGE accumulates cross-task memory of skills, statistical evidence, and recurring errors to let LLM agents achieve top-ranked performance on molecular property prediction tasks with reduced or zero test-time search.
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A Versatile AI Agent for Rare Disease Diagnosis and Risk Gene Prioritization
Hygieia is a new AI agent system that integrates phenotypes, genetics, and records to achieve superior rare disease diagnosis and gene prioritization with confidence scores.