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arxiv 2505.14030 v3 pith:ZEJ44QDR submitted 2025-05-20 cs.RO

AutoBio: A Simulation and Benchmark for Robotic Automation in Digital Biology Laboratory

classification cs.RO
keywords roboticautobiobenchmarklaboratorymodelsresearchsimulationautomation
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
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Vision-language-action (VLA) models have shown promise as generalist robotic policies by jointly leveraging visual, linguistic, and proprioceptive modalities to generate action trajectories. While recent benchmarks have advanced VLA research in domestic tasks, professional science-oriented domains remain underexplored. We introduce AutoBio, a simulation framework and benchmark designed to evaluate robotic automation in biology laboratory environments--an application domain that combines structured protocols with demanding precision and multimodal interaction. AutoBio extends existing simulation capabilities through a pipeline for digitizing real-world laboratory instruments, specialized physics plugins for mechanisms ubiquitous in laboratory workflows, and a rendering stack that support dynamic instrument interfaces and transparent materials through physically based rendering. Our benchmark comprises biologically grounded tasks spanning three difficulty levels, enabling standardized evaluation of language-guided robotic manipulation in experimental protocols. We provide infrastructure for demonstration generation and seamless integration with VLA models. Baseline evaluations with two SOTA VLA models reveal significant gaps in precision manipulation, visual reasoning, and instruction following in scientific workflows. By releasing AutoBio, we aim to catalyze research on generalist robotic systems for complex, high-precision, and multimodal professional environments. The simulator and benchmark are publicly available to facilitate reproducible research.

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Cited by 8 Pith papers

Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score.

  1. Labimus: A Simulation and Benchmark for Humanoid Dexterous Manipulation in Chemical Laboratory

    cs.RO 2026-06 unverdicted novelty 7.0

    Labimus is the first benchmark for humanoid dexterous manipulation in organic chemistry laboratories, exposing a gap between task completion and required experimental precision.

  2. SpatialWorld: Benchmarking Interactive Spatial Reasoning of Multimodal Agents in Real-World Tasks

    cs.AI 2026-06 unverdicted novelty 7.0

    SpatialWorld is a new multi-simulator benchmark showing top multimodal agents achieve under 18% success on interactive spatial tasks requiring active exploration and long-horizon planning.

  3. BiCoord: A Bimanual Manipulation Benchmark towards Long-Horizon Spatial-Temporal Coordination

    cs.RO 2026-04 conditional novelty 7.0

    BiCoord is a new benchmark for long-horizon tightly coordinated bimanual manipulation that includes quantitative metrics and shows existing policies like DP, RDT, Pi0 and OpenVLA-OFT struggle on such tasks.

  4. ST-BiBench: Benchmarking Multi-Stream Multimodal Coordination in Bimanual Embodied Tasks for MLLMs

    cs.RO 2026-02 unverdicted novelty 7.0

    ST-BiBench reveals a coordination paradox in which MLLMs show strong high-level strategic reasoning yet fail at fine-grained 16-dimensional bimanual action synthesis and multi-stream fusion.

  5. DexVerse: A Modular Benchmark for Multi-Task, Multi-Embodiment Dexterous Manipulation

    cs.RO 2026-07 conditional novelty 6.0

    A modular benchmark of 100 dexterous manipulation tasks across 3 arms and 6 hands with 3,180 demonstrations reveals that current policies (Diffusion Policy, DP3, OpenVLA, π0.5) achieve only 34% mean success, exposing ...

  6. An Embodied Simulation Platform, Benchmark, and Data-Efficient Augmentation Framework for Wet-Lab Robotics

    cs.RO 2026-06 unverdicted novelty 6.0

    Pipette supplies an open wet-lab simulation platform, 11-task benchmark, and perturbation-based augmentation pipeline that raises VLA success rates on sample handling and device tasks from limited demonstrations.

  7. RoboTwin 2.0: A Scalable Data Generator and Benchmark with Strong Domain Randomization for Robust Bimanual Robotic Manipulation

    cs.RO 2025-06 unverdicted novelty 6.0

    RoboTwin 2.0 automates diverse synthetic data creation for dual-arm robots via MLLMs and five-axis domain randomization, leading to 228-367% gains in manipulation success.

  8. Trans2Occ: Voxel Occupancy Estimation and Grasp for Transparent Objects from Simulation to Reality

    cs.RO 2026-06 unverdicted novelty 4.0

    A simulation-trained model predicts voxel occupancy from single RGB views for transparent object grasping and transfers to real robotic setups without fine-tuning.