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arxiv 1610.06461 v1 pith:BGA7BIHH submitted 2016-10-20 stat.ML cs.CVcs.ITmath.DSmath.ITmath.STstat.TH

Efficient Estimation of Compressible State-Space Models with Application to Calcium Signal Deconvolution

classification stat.ML cs.CVcs.ITmath.DSmath.ITmath.STstat.TH
keywords algorithmsapplicationcalciumcompressibledeconvolutionefficientestimationinnovations
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In this paper, we consider linear state-space models with compressible innovations and convergent transition matrices in order to model spatiotemporally sparse transient events. We perform parameter and state estimation using a dynamic compressed sensing framework and develop an efficient solution consisting of two nested Expectation-Maximization (EM) algorithms. Under suitable sparsity assumptions on the innovations, we prove recovery guarantees and derive confidence bounds for the state estimates. We provide simulation studies as well as application to spike deconvolution from calcium imaging data which verify our theoretical results and show significant improvement over existing algorithms.

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